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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b270784a6514388f119932f5ba44ce88ff8b248e908cb13c4027317e78bf7653' 
  AND token = '3a5Cq8S6IwkJ1C5rT3cicyAj7gYIAIDQAGqpVEXsnwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}