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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5906d79f77e7efc30f62f5072722da00f59b8cd731ec63bc669b3dcaeeca6d1' 
  AND token = 'JADr6p5p7bQi7besmrurAEgeOGGai/YGVK3JdVjWeCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}