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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46c08884d65731e2478378ecfafdc4571f3c6210e49f3764ddd57b9dfeb0215' 
  AND token = '/XK8liZ+6nmjpkc0xp5VJqEP2uMP7Sn5vyVG88RtS8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}