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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0365a7ff0f77012a22c19ee6f50c7cacf35df4d06becbfac4b5131fa0c42c3' 
  AND token = 'es2rGimVZ6+Kuix2B1urvQV8Eqtc5+gahwljHstttao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}