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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca490b9cb71cff2369890add9ee1b0f43440ce32aeff06cdd92d926c88c5a5a2' 
  AND token = 'b2U0bgT0GQ7iukI3FX5+PCvxKisG0qCLY1+5FfBbFfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}