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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea0b356763cde0be15ef5e3ad7fd7e225270a444e2ac7cd25a2e2f5ecb33f95' 
  AND token = 'QFmnb4KAD3bEkuHD4O7c5nECwAlfzENXCQQ+XFfquuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}