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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05df8ac26b80f5f1d73efeb2ceded2eb1f1e052671d7b0e230d6ea86a479bace' 
  AND token = 'FHaUyUD6LHgvOnYxrvaeHK2yNIvW+GNGtWBWMPYo4EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}