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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44aebda9422915d8826ccd94c434522f5d7f1ad54e728955afb535894c6bc646' 
  AND token = 'YDInX345UT8X0nx3AXDga79oH2pC8utwzv2wUbqBqo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}