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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c6b1fbd3c19928b6f9194dc9c4dee12939bcae66e857d5ad7a8140f8b8e213' 
  AND token = 'RNusm8LYNWBi9AVybJVaKZm18eWnbk9/lIJShi8B1Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}