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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6222d2d0736356bb417f7812943b41914da27d8926d91fea3d57666a63880560' 
  AND token = '6zpxYImM0Op1lUaNF3ek+LgG1phacue/MhCIQD02mPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}