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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9371f352c74fc33797dd9e9a481c2734afe7cfcf565bfe764f2e8e7ed99e50' 
  AND token = 'kYQm2XJ2RengwtefXsTFhRPIvajmVo6d6w33vtW2X5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}