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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a7264b0cbe5c173d457f2556d1e2d3fc6454ec48324466154364743be77c62' 
  AND token = '0WJw//x4x+b0to2La917i8t28y7vlkM5lO22YpqICdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}