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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b394ea4f7d18dbbfeb0e343d95d37882ad40d364cd306358bac63e90edc5bc94' 
  AND token = 'w7iE9gspEFats+U+Ov0UY+Bd8gqXbH/e9d4ZUUO8eY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}