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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d7324bd4a507d4d835d095173d4ec52c7ff92950246660901f320e80cf3e3a' 
  AND token = 'VD9eWdPpjGUf4K0X9rtXDJ2bQqFCYqgby6D70sMM46c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}