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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1af1380f43de569268483df3aa8fdf900a3b5acbb997349461dd611f6c5c8f' 
  AND token = 'OUC5n0Mh4U/B2pYRrnWy530Uobx0MXNcl/n9Ea9Itm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}