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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5573c1b5bf626f24c076d6cf9f26a4ca2a67582b95acd0d59160e8797a6df9fe' 
  AND token = '00ZW2RgR8NC3avZxEJhLMmWOEmMcDnPAiH5XRwoz8wE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}