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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f631bb38ae8f17980ac4005cfc994b0fb9ccac9c611aaf796ba1490600fb253' 
  AND token = 'ubKuxl0rdTg4/c4mqoSU9mCEtbJiuTL0UyMsRm5M8Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}