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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b643bb966347ba8e1da7a86d917135379f4b16ddd3a16ac499a657c81c2416' 
  AND token = '25q6od+sQZw1n+yxSsLO+5bapF2CeRwycLs8ZlZMaAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}