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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '791b2bc854aaa04601719cc753debf4fe191280f5fe62b1c6f1540161f1cc484' 
  AND token = '0x6m54SxOIz/RHVhvQNLeCBVmCSr3ic7nJxwDm4KPWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}