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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '156875924a6a7301d6b545cbfa89a79b5aae1d74d1e45b384957fcb07e30be08' 
  AND token = 'tgE4EDkzR1oLx8WxA73BqC3qabPPZ+HbUKLQNPz8eGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}