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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1711067e79367b4015e6add00907583c0ce0d8010d4978dbacca7e6923d8c0b' 
  AND token = 'zHcH5xn0WKAtOqmaxPDPynx2pmAWjmkkkDXx60Ghe1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}