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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0657e519b1f71e601b9876417b5ab5162b7b099761060d00b3bf91cedb955750' 
  AND token = 'NwUwI3MrlnAxeOQLvRHgwsHCphxIxjOmqd8AN+Ku0EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}