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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1bf218a62737503120b6ab958ce502b13857bf24e44441fc9e8f3c09e8f589' 
  AND token = 'yiOOAg6b0MteBKl3k5yENPt0qAkZwyUpxe2+xD9vPLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}