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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5e976efff2752f0842f889167342e2c62048113f86a02984b6b9c26b7f79e6' 
  AND token = 'uF5p+M0elDL8/abgDwP+oA1+SsqgEMIy8TgnuuHdAxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}