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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2c7c2e062ece39f18e91dadeccd96e932055498066cc508c4e6349b26607906' 
  AND token = 'BeU/D8ykmCV0DccD4lKAtR+gnanWJF2pAWoT45JDnLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}