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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b039e4b3f9146d9b49d48c489b38aad452708a859a3b71a9e5284412bc9ce75' 
  AND token = 'ESlJXtBoiEjbQXwPKIHyjBaIZRGJSX7gOcJGP9xsneM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}