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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6436aa9020d2c840f017632f6d20f42351f797f55c108a31ad220ab1a25647ce' 
  AND token = 'g03RB2ksPYd7Hxi1yb5pFCBP04FRQccTTRAU3ktUMfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}