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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5495bd4e8514e11906a361fe8efe76c386bdaf69b577cecd963f97368dd6f1e2' 
  AND token = 'Ne7d9Hw+gzY0fyHH7ckAD2AlyT67kCgz4x/SozDKRVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}