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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defc775361666e1eea40efc2aab50f5d5372f1ce405a73be4292a1db4a8c8c12' 
  AND token = 'sM/ztE7NrJ7VRmcRSP/797g1aNADNqoXhVIJKiLdr0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}