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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59dddbf2d979baa721cb8c56b879b4bb7e5393d5fd45a424f65eb4145687259' 
  AND token = '3YtSGUID+m6Zg8VRWnzlReCqSdd7MMtd+SO+DoSVFoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}