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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d5aabfe5d92b558b976df4100646ec7aca9716cf60017d2a60eadfc95d900db' 
  AND token = 'j3Fl8OXY+DqfWUV+96SUaoHpxgZM+kvA7Yrono3AQHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}