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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac10768f9b1f3a9a33c44df2792d6fa87085ea99d68c1777d09c5a2345e069ae' 
  AND token = 'Jf8bTf0QDOsBHFxskspsq0A/KEUXg7ddyQQ4LTJBFMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}