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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '687146c4ca150cbdb00e027122846c67775dc13e972493ae46f6a7b313f1fdd7' 
  AND token = 'PrLcOI/sDt6jV/3lXnn88cY2+9UYz+VeoD49taZYcEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}