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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8136511218807bede64c8f2a4374c2965557028e67dc57536b8d53a0e2593f03' 
  AND token = 'GVlPWPv+OPdy+yXmNSSp7NHS4AMj2NkeV9Z4bPzvRZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}