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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a726b948f07babea0917d31587c63c24d482ea60ad693feb3109f6d55d0400' 
  AND token = '0PCafEEBM45ajZtOlb347KdVwGb6k4SGRqlAm7wAh14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}