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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049be8a44a247b758b56874c1cfe507d7dc11f7433b9c75cd162e4bb1cc6763e' 
  AND token = 'N16putv76KLPQYDpsvf1tNrHxK2uUTDn136WLzKr8m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}