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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8437f4aa5b7046c617b18de8f0f54782d453122f0cc88a38a0d110cc402b0cd8' 
  AND token = 'XAgFTXv4KNb4WnIIZIl2+p69yZ+GmtZAb9Wbq1R8NDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}