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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b16420bcc0578480c58e8dc2921438423b4379b91b82b72a730e8952f5981c2' 
  AND token = 'khD+rgh+BNVabS46GV339mMeAROgUAZ9EkqmNSdiNq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}