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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e888f49229539e1ae0a9129d19ec63e0c16e73a1c8690b9c67d338cc96193679' 
  AND token = 'EjZkX992hzswvB9H/Cm787cMZnyedqNSDfLACqd4DSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}