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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc22f246f7e6b0762c0298ecc3a51040f05a01d4f2352812f0e67876ab9e091c' 
  AND token = 'CzzobvqAr3mo1t56N+JdNwLmnlZ8/Sf+P9xhjjJf3ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}