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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ffbf8b762ce3c791e6c9294cd4b81d26d899ed816f94f48da727dea5bbc714' 
  AND token = 'oOuIcVHTNNU5EM6bqbjK6hRjzqFZAPgzhDi6bXuZhRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}