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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19423f9ca46c9280c6310ec2b2ab0271f5975c161d91763bf400aa48414519e' 
  AND token = 'PCWFv+re0/8NHOfjzMe+Vm9TsKg+EZRB4dMa61DaOYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}