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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b91ab5d60a06dd67d273d274f7b1507fb79beb43bd17cf9d81e3e6fd259d1c' 
  AND token = 'V0rnVKgVM7WOoNPe3eqG7si9Uye/ETW9+UQ/gD/KE6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}