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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0882ef2f33457bb31d854d1b080b7bfd9305dd38de16df79d24dc458d84e1d06' 
  AND token = 'eU5hq7dogqxaZ1viKsShkXRZCVkNTYzHLNRonGJfcFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}