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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eed22b86fefa078cd4816e1fd4a9c3e464f065792d36d77a31270d2d33f5ee4' 
  AND token = 'XoDnBe38aOM8ixBLhNd3pdPRNLELyo2Uj+jSGTNnlPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}