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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916b9626f9856cb27785e70983860b657b7082fb3ba8712d5de725544a97b956' 
  AND token = 'Tdx0Z6lgrgf6V+5Ys49qVhuyYEA6uL4mL0IBVt+xy9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}