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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc36dde582003bbd5cad8ccc8bf447fe75d7978f27d83d816d7b2c9ac7a3f99' 
  AND token = 'xLzHBPbf0FtpsxGtUX92y+/Kb29e84vtX/R2bhK6IJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}