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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4758486da258558859eb5652a0da1fb6f2594a2ef0e1ff5d92b9704e3afee3' 
  AND token = 'qY8zOmXRiLWxMDoxmhBhwC13v24rf8nRYNsC4J6PnRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}