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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549a83a7a00cef800ec9ebace8afff9f498aee10b7da46cf253d3a81e119b1ec' 
  AND token = 'NfWc/SB492KTBHtwQQGBK3oAiDQGiCtaZKPiNnU/Nl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}