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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1f45995ab15bd7945d42bb3d1c9ce1716feb7cc1e9a1812221a5cb0259d924' 
  AND token = 'iElGMjmaYU2KOEyf8dhoaPzA9TFeWn0fM/sFASA6eHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}